Correlative microscopy for structural microbiology

Advances in labelling, workflows and instrumentation areis described targeting the field of microbiology.

Understanding how microbes utilize their environment is aided by visualizing them in their natural context at high resolution. Correlative imaging enables efficient targeting and identification of labelled viral and bacterial components by light microscopy to be combined with high-resolution imaging by electron microscopy. Advances in genetic and bioorthogonal labelling, improved workflows for targeting and image correlation, as well as large-scale data collection are increasing the applicability of correlative imaging methods.

Howes SC, Koning RI, Koster AJ. Correlative microscopy for structural microbiology. Curr Opin Microbiol. 2018 Jan 29;43:132-138. [Epub ahead of print]  PubMed PMID: 29414444


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