Prof.dr.ir. Koster (1960) is head of the Section Electron Microscopy in the Department Cell and Chemical Biology at the Leiden University Medical Center (LUMC) since January 1st, 2006. Since May 1st, 2008, he is full professor on Ultra-structural and Molecular Imaging appointed by the Leiden University.
In 1989 Bram Koster obtained his PhD Physics degree at the Delft University of Technology on the mathematical modelling and automation of transmission electron microscopes. Between 1989 and 1991 he worked as a Project Manager and Software Developer at Tietz Video and Imaging Processing (TVIPS, GmbH) in Gauting, near Munich, Germany. From 1991 to 1993 he was a post-doc in the group of David Agard, at UCSF, San Francisco working on the automation electron tomography. From 1993 to 1997 he was a post-doctoral fellow in the group of Wolfgang Baumeister at the Max-Planck-Institute for Biochemistry in Martinsried, near Munich, Germany, where he worked on low-dose cryo tomography method developments. In 1997 he returned to the Netherlands to the group of Arie Verkleij at Utrecht University, where he became Associate Professor and set up his own group aimed at method development for the 3D imaging electron microscopy specimen. From 1998 to 2003 he was a Fellow of the Dutch Academy of Sciences (KNAW). Jan 1st, 2006 he went to the Leiden University Medical Center to head the section Electron Microscopy. Between September 2015 and November 2018 he was appointed Professor Nanobioimaging at the Faculty of Science (Leiden University) and Scientific Director of the Netherlands Center of Electron Nanoscopy (NeCEN) also located in Leiden.
Bram Koster enjoys working on the application and development of advanced electron microscopy methods, in particular on the combination of high-resolution light microscopy with 3D electron microscopy.