The Netherlands Center for Electron Nanoscopy (NeCEN) is the Dutch advanced cryo-electron microscopy facility situated at the Institute Biology Leiden (IBL) at Leiden University (UL) in Leiden, the Netherlands. It specializes in data collection for high-resolution structure determination of single particle analysis of proteins and viruses and in data acquisition for cryo-electron tomography of protein complexes and bacteria.
NeCEN offers access to two highly sophisticated 300 kV cryo electron microscopes (FEI Titan Krios). One specifically equipped for cryo electron tomography, including an energy filter and K2 direct electron detector, and one for single particle analysis cryo electron microscopy, with Cs corrector and Falcon direct electron detector.
The NeCEN is located in close vicinity to our laboratory and our in-house workflow is compatible with the requirements for the Titan Krios microscopes. We have facilities for remote access and remote microscope monitoring. Though the access to NeCEN is arranged independently, it could be effective for you if we could help carry out pilot research projects on a collaborative basis.